Abstract

Objectives: The burden of hospital admissions for acute pancreatitis (AP) has significantly increased in past few years across the globe. In severe form it is one of the deadliest diseases of hepatobiliary system. Acute pancreatitis is a noticeable health issue which leads more than million hospital admissions in USA per year. The incidence of this disease in young age group has also increase dramatically. The purpose of this study was to identify the causes, severity and outcomes of AP in young population. Study Design: A Prospective, cross-sectional study Setting: Surgical Unit 1 Holy Family Hospital, Rawalpindi, Pakistan Study Duration: June 2014 to March 2017 Materials &Methods: \All patients between 12 and 25 years with clinical features of Acute Pancreatitis, having serum amylase greater than three times the upper normal limit or raised lipase levels, were included in our study. Causes, clinical features, severity and outcomes of acute pancreatitis were evaluated. Results: A total A total of 78 patients were included in our study out of which 63 (80.8 %) were female and 15 (19.2 %) were males. Gall bladder stones were the main cause of pancreatitis in 54 (69%) patients followed by drugs in 13 (17%) patients. Contrast enhanced computerized tomography scan (CT scan) done between 24 to 48 hours of presentation showed 30 (38.5%) patients had necrotizing pancreatitis whereas 48 (61.5 %) patients had interstitial pancreatitis. The organ failure which was predominantly pulmonary system occurred in 15 (19.2 %) of patients All 78 patients were discharge from hospital without any mortality. Conclusion: In resource limited countries acute pancreatitis is posing a great burden to emergency as well as outpatient departments of tertiary care hospitals. This study concluded that etiology of acute pancreatitis is significantly different in young age group although the predominant causative factor is still gallstones

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