Analysis of abnormality of ST segment resolution in patients with acute ST-segment elevation myocardial infarction post percutaneous coronary intervention

Abstract

Objective To evaluate the correlation factors of the abnormality of ST segment resolution after percutaneous coronary intervention(PCI)in patients with acute ST-segment elevation myocardial infarction(STEMI). Methods Consecutive 127 STEMI patients from January 2009 to August 2010 in XuanWu Hospital whose TIMI flow was stage 3 post emergency PCI were enrolled in this study.Participants were divided into two groups depending on ST segment resolution(STR), complete STR group with STR≥50% and incomplete STR group with STR<50%.Clinical outcomes were compared between two groups.Risk factors associated with STR were analyzed. Results Baseline comparison of two groups showed that heart rate of incomplete STR group was higher than complete STR group(80.3±11.9 vs. 73.3±17.5, P=0.023). The other parameters were not significantly different between the two groups(all P>0.05). Multivariate analysis showed that the onset of symptom to balloon coronary artery opening time(OR: 0.998, 95% CI: 0.996-0.999, P=0.014)and left coronary artery obstruction(OR: 0.341, 95% CI: 0.122-0.951, P=0.040)were independent predictors for incomplete STR. Conclusions Time of reperfusion and anatomic site of coronary lesion may be associated with incomplete STR. Key words: Acute Coronary Syndrome; ST segment resolution; Left coronary artery