Abstract

For patients with diabetes, suboptimal medication adherence contributes to disease progression, complications, and increased healthcare costs. Identification of, and intervention for patient-identified reasons for nonadherence are essential to improving medication adherence. This prospective, quality improvement study was conducted at an independent community pharmacy in the Mid-West United States. Patients with a proportion of days covered (PDC) for their oral antidiabetic medications of less than 80% were contacted by telephone and interviewed by a clinical pharmacist. The interviews and corresponding adherence interventions were guided by an abbreviated version of the Drug Adherence Work-Up (DRAW©) tool that focused on oral medications for diabetes. The change in PDC 120-days post-interview was assessed to determine the change in adherence rates. Patients receiving the pharmacist-delivered adherence intervention had significantly higher 120 day PDC values which are likely to indicate more regular medication-taking at home. Almost half of study patients signed up for medication synchronization and these patients trended toward higher PDC values, although the relative difference was not statistically significant from those receiving the intervention and not opting to have their medications synchronized.

Highlights

  • As of 2015, over 30.3 million Americans have a diabetes diagnosis, and another 84.1 million have prediabetes

  • Medication non-adherence is common among patients with type 2 diabetes who are taking oral antidiabetic medications

  • At the initiation of the study, a query using a third party software platform for facilitating pharmacy quality improvement identified 96 patients taking at least one oral antidiabetic medication and who had a proportion of days covered (PDC) for their oral antidiabetic medications of less than 80%

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Summary

Introduction

As of 2015, over 30.3 million Americans have a diabetes diagnosis, and another 84.1 million have prediabetes. In 2012, total direct and indirect costs of healthcare for patients with diabetes was estimated at $245 billion with average annual medical expenses of $13,700 per patient. In 2014 alone, 14.2 million emergency room visits and 7.2 million hospitalizations were for patients with diabetes [1]. While diabetes prevention is important, for those already afflicted, adherence to recommended medications can lower the risk of being hospitalized or visiting the emergency room by 13% [2]. Medication non-adherence is common among patients with type 2 diabetes who are taking oral antidiabetic medications. Common reasons for medication non-adherence among patients with diabetes include forgetfulness, concerns about side effects or harm from medicines, and cost [4,5]. The stigma associated with taking medications, paired with the fear of medication-related complications can cause apprehension about taking medications as prescribed [4,5]

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