Abstract
BackgroundThe aim of this was to analyze 4 chest CT imaging features of patients with coronavirus disease 2019 (COVID-19) in Shenzhen, China so as to improve the diagnosis of COVID-19.MethodsChest CT of 34 patients with COVID-19 confirmed by the nucleic acid test (NAT) were retrospectively analyzed. Analyses were performed to investigate the pathological basis of four imaging features(“feather sign”,“dandelion sign”,“pomegranate sign”, and “rime sign”) and to summarize the follow-up results.ResultsThere were 22 patients (65.2%) with typical “feather sign”and 18 (52.9%) with “dandelion sign”, while few patients had “pomegranate sign” and “rime sign”. The “feather sign” and “dandelion sign” were composed of stripe or round ground-glass opacity (GGO), thickened blood vessels, and small-thickened interlobular septa. The “pomegranate sign” was characterized as follows: the increased range of GGO, the significant thickening of the interlobular septum, complicated with a small amount of punctate alveolar hemorrhage. The “rime sign” was characterized by numerous alveolar edemas. Microscopically, the wall thickening, small vascular proliferation, luminal stenosis, and occlusion, accompanied by interstitial infiltration of inflammatory cells, as well as numerous pulmonary interstitial fibrosis and partial hyaline degeneration were observed. Repeated chest CT revealed the mediastinal lymphadenectasis in one patient. Re-examination of the NAT showed another positive anal swab in two patients.Conclusion“Feather sign” and “dandelion sign” were typical chest CT features in patients withCOVID-19; “pomegranate sign” was an atypical feature, and “rime sign” was a severe feature. In clinical work, accurate identification of various chest CT signs can help to improve the diagnostic accuracy of COVID-19 and reduce the misdiagnosis or missed diagnosis rate.
Highlights
The aim of this was to analyze 4 chest CT imaging features of patients with coronavirus disease 2019 (COVID-19) in Shenzhen, China so as to improve the diagnosis of COVID-19
A baseline chest CT scan was abnormal in 34 patients (Table 2); (67.6%) showed lesions involving both lungs, and (70.6%) reported bilateral multifocal
In the present study, we found that the most common CT imaging features in patients with COVID-19 were: bilateral, multifocal ground-glass opacity (GGO), peripheral distribution; the predominant lower lobe; pleural effusion and lymphadenectasis were rare, which is consistent with previous reports [6,7,8]
Summary
The aim of this was to analyze 4 chest CT imaging features of patients with coronavirus disease 2019 (COVID-19) in Shenzhen, China so as to improve the diagnosis of COVID-19. Since the COVID-19 outbreak in December 2019, the number of confirmed cases has been rapidly increasing. (March 15, 2020), COVID-19, has spread to 146 countries and territories across six continents, infecting more than 164,000 and killing more than 6,400 people. COVID-19 is considered one of the worst epidemics in human history. The COVID-19 is a lineage B betacoronavirus. According to the internationally published virus classification, there are nine types of this betacoronavirus [1], among which mouse hepatitis virus, rousettus bat coronavirus HKU9, and severe acute respiratory syndrome (SARS) are the most widely known. On February 11, 2020, the International Committee on Taxonomy of Viruses named COVID-19 as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
