Abstract

ObjectiveThe present study aims to analyze the main reasons that lead to the failure of bone tuberculosis (TB) surgery and the efficacy of reoperation.MethodsA total of 3,000 cases of bone TB patients were examined retrospectively. Of these, 180 cases had recurrence, including 135 cases of spinal TB and 45 cases of limb TB. Preoperative indicators of duration of anti-TB chemotherapy, nutritional conditions, temperature conditions and erythrocyte sedimentation rate, and medication time of postoperative and recurrence were statistically analyzed.ResultsOf all 180 cases with reoperation, 176 cases were cured, and four paralyzed patients were symptomatically improved. The causes of postoperative recurrence of bone TB were relatively complex. Efficacy of reoperation was evaluated. Shorter chemotherapy duration, long-term illness, poor health, a higher body temperature, and an accelerated ESR are likely to increase the risk of recurrence.ConclusionsGiven the operation failure, careful analysis of the failure reasons and the targeted reoperation can obtain satisfactory results, thereby avoiding the failure of the initial surgery.

Highlights

  • Tuberculosis (TB), which is one of the major infectious diseases in the world today, has caused a huge threat to human health

  • Analysis of the causes of reoperations Causes of reoperation were complex through the analysis of patients with bone TB

  • 72.2% received operations after 1 week of administration, 17.2% in 2 weeks, and 10.6% in 4 weeks, demonstrating that the risk of recurrence increased with shortened chemotherapy duration

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Summary

Introduction

Tuberculosis (TB), which is one of the major infectious diseases in the world today, has caused a huge threat to human health. About one third of the human population is infected with mycobacterium TB, with about 800 million new infections and up to two million deaths caused by TB each year. With the rapid growth of the global population, the acceleration of the population flow, and the human immunodeficiency virus (HIV) infection, morbidity of TB has been increasing every year [1,2,3]. The threat of drug-resistant TB is increasing. Lung TB accounts for the vast majority of the proportion of drug-sensitive and drug-resistant TB. TB research has focused on lung TB, while those on bone TB are fewer. Bone TB is a chronic disease, which

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