Abstract
A. bisporus mushrooms are well known for their nutritional and medicinal values. A. bisporus is a source of protein (about 40% on dry basis), ergo sterol, a precursor of vitamin D, several minerals, carbohydrate and fat. In the present investigation studies were conducted on the effect of A. bisporus (U-03) extracts on human pathogenic bacteria in-vitro condition. Highest antimicrobial activity was observed in methanol extract (19.5%) against P. aeruginosa as compared to ethanol extract (11.25%). Similar results was obtained for S. aureus (16%) and B. cereus (13%) in methanol extract. Least microbial growth inhibition was observed in B. cereus (13%) followed by P. aeruginosa (11.25%) with respect to control in ethanol extract. Highest antimicrobial activity with ethanolic extracts was recorded against S. aureus (18.42%) as compared control and other tested bacterial isolates. No antimicrobial activity observed in P. aeruginosa in ethanol extract but least inhibition was observed in methanol extract (20mm). The present study has shown that the extracts of the A. bisporus mushrooms have shown promising antimicrobial activities against the tested organisms.
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