ANALYSING ANTIDEPRESSANT USE IN DEPRESSION OUTPATIENTS AT DA NANG PSYCHIATRIC HOSPITAL

Abstract

Background: Depression is a common psychiatric disorder worldwide as well as Vietnam, greatly affecting the quality of life and threatening patient lives due to the high risk of suicide. Early treatment and appropriate use of drugs will help improve the effectiveness of treatment and reduce the burden on public health. Objectives: To analyze antidepressant use and level of drug interactions encountered in depression outpatient. Materials and methods: 252 depression outpatients at Da Nang Psychiatric Hospital, cross-sectional description method. Results: The multivalent treatment regimen was initiated on admission in 92.1% of cases, SSRI group accounted for the highest proportion (45.6%), followed by TeCA, TCA and SNRI, at 37.9%; 16.2% and 0.3% respectively. In the SSRI group, Fluoxetin was administered for 110/166 cases (66.3%); followed by Sertralin 31.9%; Fluvoxamin and Escitalopram accounted for only 1.2% and 0.6%, respectively. Out of 480 times using supportive medicine group, the highest percentage of patients using antipsychotic drugs (51.0%), including: Olanzapine, Sulpiride,... The number of patients being administered rational drug was 223/252 cases (88.5%). The results of drug interactions are largely severe. Conclusions: Antidepressants indicated in accordance with the recommendation accounnted for a high proportion and drug interactions appear in prescriptions at a high rate (50.8%) and are mostly severe. Key words: Depression, antidepressants, antidepressants use, drug interaction