Analiza kliniczno-epidemiologiczna wyników leczenia chorych z rakiem krtani w Oddziale Otolaryngologicznym Wojewódzkiego Szpitala Specjalistycznego w Rzeszowie w latach 1996–2005

Abstract

Cancer of the larynx is an important epidemiological and oncological problem.According to the National Cancer Registry, 2075 new cases of laryngeal cancer were recorded in 2008 in Poland, which accounts for approximately 50% of malignant head and neck tumours.The modality of treatment and prognosis depend on the primary location of the tumour and the advancement of the symptoms. The main objective of the study was to evaluate the treatment results among patients with laryngeal cancer who were treated surgically and in combination with radiotherapy in the Departments of Otolaryngology and Radiotherapy at the Voivodal Specialist Hospital in Rzeszów between 1996 and 2005.The detailed objectives are 1) impact assessment of selected epidemiological factors on clinical outcomes and prognosis; 2) the risk of locoregional recurrence, depending on the chosen clinical and histopathological features.The clinical material consists of 359 patients diagnosed with laryngeal cancer and treated at the Otolaryngology Department of Voivodal Specialist Hospital in Rzeszow, Poland between 1996 and 2005. ConclusionsThe results of surgical treatment of patients with laryngeal cancer treated between 1996 and 2005 are comparable with the data which are published at present: 5-year survival of 58.5% and 10-year survival of 38.5% of in the examined group of patients.1.Gender and the habit of smoking were not factors affecting the survival rate after the surgery.2.Lower degree of cancer differentiation reduces significantly the probability of survival and shortens the period of survival after the surgery.3.Histological type of cancer does not affect the survival period, probability of survival and the proportion of surviving patients.4.The percentage of those surviving and the probability of survival among patients treated surgically for laryngeal cancer in clinical stage I is significantly higher than compared with clinical stage II, III and IV.