Analiza efikasnosti ropivakaina sa deksametazonom u oralnoj hirurgiji

Abstract

Introduction: Prolonged local anesthesia is achieved by using long-acting local anesthetics, as ropivacaine and bupivacaine. In different surgical branches, longer absence of pain is noted after surgical intervention when ropivacaine is used with dexamethasone than when it is used alone. The aim of the study was to determine the effect on the duration of local anesthesia with a combination of 0.75% ropivacaine with the addition of dexamethasone during oral surgery interventions. Material and methods: A total of 12 patients participated in the study which was conducted at the Department of Oral Surgery at The Dentistry Clinic in Niš, in 2017.Surgical interventions were performed on both upper and lower jaw. Patients were divided into 2 groups: the study group of 6 patients who received 4 ml of 0.75% ropivacaine solution with addition of 1 ml/4mg dexamethasone and the control group of 6 patients who received 4 ml of 0, 75% solution of ropivacaine without the addition of dexamethasone. Statistical data was processed by the SPSS 15.0 software. The results: The onset time of first signs of anesthesia, confirmed by testing sensibility of soft tissues (lip and gingiva), was 1,5 min in the study group and 2.66 in the control group. The time necessary for the full effect of anesthesia to set in, i.e. total insensitivity of soft tissues, was 3.5 min in the study group and 4.66 min in the control group. The duration of local anesthesia was 625,5 min in the study group which is considered statistically significant (p < 0.01) and 290 min in the control group. Conclusion: Small doses of dexamethasone added to local anesthetics may reduce the need for additional anesthesia and analgesic therapy within the first 24 hours after major oral surgery interventions.