Abstract

Cost-effectiveness analysis of ceftriaxone and cefotaxim prophylactic antibiotics of appendectomy in PKU Muhammadiyah Hospital Yogyakarta from January 2006 to December 2007 has been studied. This study was aimed to explore the direct medical cost, cost-effectiveness ratio, and determine whether drugs of ceftriaxone or cefotaxim whose had more effective cost. This study was carried out by descriptive retrospective design. The population was all inpatients of appendectomy getting prophylaxis antibiotics with either ceftriaxon or cefotaxim therapy in PKU Muhammadiyah Hospital Yogyakarta. The population target were the appendectomy patients in the third class of PKU Muhammadiyah Hospital Yogyakarta from January 2006 to December 2007. The result indicated that direct medical cost of the patients getting ceftriaxone therapy was Rp 422.257, whereas the cost of the patients getting cefotaxim therapy was Rp 487.680. Cost-effectiveness ratio of whom getting ceftriaxone therapy was Rp 105.564/day, whereas the ratio of whom getting cefotaxim therapy was Rp 162.560. Finally, it have not been able to determine which drug is more cost-effective.

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