Abstract
We compared the analgesic effects of continuous and frequency-modulated red and infrared LEDproduced polarized light (PL) measured in a formalin test model. The control group consisted of 20 albino mice, while the six experimental groups included 10 animals each. Red LED PL (637 nm) was found to be more effective in suppressing pain than infrared light (860 nm); when PL was applied to the locus of pain, the average normalized intensity of analgesia was 43.6 and 12.9%, on average, respectively. This difference was not due to a dissimilarity in the radiation power density (26.5 and 25.4 mW/cm2) but rather to the unequal wavelength ranges. We also studied the analgesic effects of applications to the pain locus of red light (with no infrared component) modulated at frequencies of 10, 600, 3000, or 8000 Hz. In all experimental series where frequency-modulated PL was used, analgesia was weaker than in the case of continuous PL (43.6%). A relatively greater analgesic effect (35.2%) was recorded at the modulation frequency of 600 Hz, while the smallest (25.0%) was observed at 8000 Hz.
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