Abstract
Polyalthia longifolia leaves ethanolic extracts produced significant analgesic activity in both Hot plate and acetic acid induced writhing models in mice. In hot plate method percentage increase in reaction time was determined where as in acetic acid induced writhing model percentage decrease in writhings was determined. From the results obtained it can be concluded that Polyalthia longifolia leaves has analgesic, anti inflammatory and antipyretic activity.
 Keywords: Analgesic, Anti-inflammatory, Antipyretic, Hot plate method, Acetic acid induced writhing model.
Highlights
In India numerous invaluable plants are used in ethnomedical practices as well as in Ayurveda and sidha
From the results obtained it can be concluded that Polyalthia longifolia leaves has analgesic, anti inflammatory and antipyretic activity
The study was conducted after obtaining the approval from Institutional Animal Ethics Committee (IAEC), and the experimental procedure were in accordance to the guidelines of IAEC (No:688/02/c/CPCSEA)
Summary
In India numerous invaluable plants are used in ethnomedical practices as well as in Ayurveda and sidha. Non steroidal anti-inflammatory drugs (NSAID’s) are widely used in the treatment of pain, pyrexia and inflammation These drugs have side effects especially on the gastro intestinal tract.[2] Through this evaluation of pharmacological activities in Polyalthia longifolia leaves for analgesic, antiinflammatory and antipyretic activity in experimental animal models was taken up. The plant possesses significant analgesic, antiinflammatory and vasodepressant activities This plant is used in traditional medicine to combat fever, its antipyretic effect has not been experimentally evaluated.[4]. An attempt is made to evaluate the analgesic, antiinflammatory and antipyretic potential of the ethanolic extract of leaves of Polyalthia longifolia. Polyalthia longifolia leaves ethanolic extracts produced significant analgesic activity in both Hot plate and acetic acid induced writhing models in mice. In hot plate method percentage increase in reaction time was determined where as in acetic acid induced writhing model percentage decrease in writhing was determined
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
