Abstract
Background:Opuntia elatio Mill is a xerophytic plant with potentially active nutrients. It is traditionally appreciated for its pharmacological properties; however, the scientific information on this plant is insufficient.Objective:The present study evaluates the antinociceptive and anti-inflammatory action of prickly pear.Materials and Methods:Writhing and tail-immersion tests were carried out to evaluate analgesic action, while the carrageenan-induced paw edema and neutrophil adhesion tests were conducted in Albino wistar rats to assess anti-inflammatory action.Results:ED50 values of the fruit juice in writhing, tail immersion, and paw edema test were 0.919, 2.77, and 9.282 ml/kg, respectively. The fruits of Opuntia produced analgesic and anti-inflammatory action in a dose-dependent manner.Conclusion:The results establish the folklore use of prickly pear may be due to the presence of betacyanin and/or other phenolic compounds.
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