Abstract

Rheumatoid arthritis (RA) is a disease characterized by chronic, progressive destruction of cartilage and bone at multiple joints and inflammation of other body organs. It affects an estimated 2 million Americans, or less than 1.0% of the U.S. population. 1 The disease can be seen in people of all ages, but peak onset is between the ages of 20 and 45. It is at least two times more common in women than in men. 1 .

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