Abstract

Future space exploration missions will take humans far beyond low Earth orbit and require complete crew autonomy. The ability to provide anaesthesia will be important given the expected risk of severe medical events requiring surgery. Knowledge and experience of such procedures during space missions is currently extremely limited. Austere and isolated environments (such as polar bases or submarines) have been used extensively as test beds for spaceflight to probe hazards, train crews, develop clinical protocols and countermeasures for prospective space missions. We have conducted a literature review on anaesthesia in austere environments relevant to distant space missions. In each setting, we assessed how the problems related to the provision of anaesthesia (e.g., medical kit and skills) are dealt with or prepared for. We analysed how these factors could be applied to the unique environment of a space exploration mission. The delivery of anaesthesia will be complicated by many factors including space-induced physiological changes and limitations in skills and equipment. The basic principles of a safe anaesthesia in an austere environment (appropriate training, presence of minimal safety and monitoring equipment, etc.) can be extended to the context of a space exploration mission. Skills redundancy is an important safety factor, and basic competency in anaesthesia should be part of the skillset of several crewmembers. The literature suggests that safe and effective anaesthesia could be achieved by a physician during future space exploration missions. In a life-or-limb situation, non-physicians may be able to conduct anaesthetic procedures, including simplified general anaesthesia.

Highlights

  • Significant plans have been drawn by government space agencies and private companies for manned spaceflights beyond low Earth orbit (LEO) in the coming years, with a focus on missions to Mars

  • The full texts of 241 publications were assessed for eligibility

  • LEO can be used as an 'in-space' analogue for interplanetary travel research.[23]

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Summary

Introduction

Significant plans have been drawn by government space agencies and private companies for manned spaceflights beyond low Earth orbit (LEO) in the coming years, with a focus on missions to Mars. Such flights have been termed space exploration missions (SEM). These interplanetary missions will present great challenges to the field of space medicine.[2,3] During the exploration of frontiers on Earth, human physiologic maladaptation, illness, and injury have accounted for more failures than technical or environmental factors.[4,5,6] Beyond the immediate vicinity of Earth, there will be no possibility for the crew to return swiftly to the ground or to be assisted in real-time from Earth.[3,7] Such space exploration will entail extreme isolation and total crew autonomy.[2,4]

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