Abstract
Juvenile idiopathic arthritis is the most common cause of chronic arthritis in children. JIA is a heterogeneous disease that has been classified by the International League of Associations for Rheumatology (ILAR) on seven different subtypes according to the most relevant clinical and serological features. Previous studies have demonstrated an association between the presence of antinuclear antibodies (ANA) and features like: early-onset oligoarticular disease, female predominance, asymmetric arthritis and higher frequency of uveitis. There are limited data on the characteristics clinical and analytical into different subtypes of JIA in Colombian children and their relationship with type of onset and clinical course.
Highlights
Juvenile idiopathic arthritis is the most common cause of chronic arthritis in children
The distribution of JIA patients according to International League of Associations for Rheumatology (ILAR) category were: systemic arthritis 23 (7.5%), oligoarticular persistent 86 (28%), oligoarticular extended 8 (2.5%), RF positive polyarthritis 21 (6.8%), RF negative polyarthritis 71 (23%), ERA
Uveitis was more frequent in antinuclear antibodies (ANA) positive patients (17% vs. 0.4% p=0.002), in oligoarthritis and in early-onset JIA
Summary
Juvenile idiopathic arthritis is the most common cause of chronic arthritis in children. JIA is a heterogeneous disease that has been classified by the International League of Associations for Rheumatology (ILAR) on seven different subtypes according to the most relevant clinical and serological features. Previous studies have demonstrated an association between the presence of antinuclear antibodies (ANA) and features like: early-onset oligoarticular disease, female predominance, asymmetric arthritis and higher frequency of uveitis. There are limited data on the characteristics clinical and analytical into different subtypes of JIA in Colombian children and their relationship with type of onset and clinical course
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