An updated review of contribution of long noncoding RNA-NEAT1 to the progression of human cancers.

Amir Anbiyaiee,Farhoodeh Ghaedrahmati,Seyed Esmaeil Khoshnam,Klaudia Radoszkiewicz,Shirin Azizidoost,Maryam Farzaneh,Tariq Masoodi,Shahab Uddin,Mohadeseh Sheykhi-Sabzehpoush,Niloofar Khoshdel Rad,Seyedeh Pardis Motiee Jooybari

doi:10.1016/j.prp.2023.154380

An updated review of contribution of long noncoding RNA-NEAT1 to the progression of human cancers.

Amir Anbiyaiee, Farhoodeh Ghaedrahmati + Show 9 more

https://doi.org/10.1016/j.prp.2023.154380

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Journal: Pathology, research and practice	Publication Date: May 1, 2023
Citations: 4

Affiliation: Ahvaz Jundishapur University of Medical Sciences, Isfahan University of Medical Sciences, Polish Academy of Sciences, Qatar Airways (Qatar), Hamad Medical Corporation, Imam Khomeini Hospital, Tehran University of Medical Sciences, Royan Institute, Academic Center for Education, Culture and Research, Gonbad Kavous University

#Nuclear Paraspeckle Assembly Transcript 1 #EMT In Tumor Cells + Show 8 more

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Abstract

Long non-coding RNAs (lncRNAs) present pivotal roles in cancer tumorigenesis and progression. Recently, nuclear paraspeckle assembly transcript 1 (NEAT1) as a lncRNA has been shown to mediate cell proliferation, migration, and EMT in tumor cells. NEAT1 by targeting several miRNAs/mRNA axes could regulate cancer cell behavior. Therefore, NEAT1 may function as a potent biomarker for the prediction and treatment of some human cancers. In this review, we summarized various NEAT1-related signaling pathways that are critical in cancer initiation and progression.

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