Abstract

Polycystic ovary syndrome (PCOS), also known as Stein-Leventhal Syndrome, was first described in 1935. PCOS, which may also be referred to as polycystic ovary disease is the most common hormonal disorder found in premenopausal women. PCOS is the most common endocrine disorder in women of reproductive age and is the most common cause of infertility due to ovulation. A PCOS is an endocrine disorder which affects the adolescent girls. A PCOS is a condition in which a woman has an imbalance of female sex hormones. This may lead to changes in the menstrual cycle, cyst in the ovary, failure to conceive, and other health problems. It is a common health problem among teenagers and young women. It affects 5–10% of women in their reproductive years. These problems cause infertility. Two principal components to diagnose this syndrome are menstrual dysfunction and clinical or laboratory hyperandrogenism in which these items are used in clinical diagnosis. PCOS is a hormonal disorder that affects between 5% and 10% of women of reproductive age and remains the most enigmatic reproductive disorders. The most common symptoms of PCOS are obesity, acne, amenorrhea, irregular menstrual cycles, hirsutism, insulin resistance (IR), and high cholesterol. Due to the varied nature of PCOS and the large range of possible signs and symptoms, health personnel need a thorough knowledge of the disorder and its management. It is a major disorder characterized by elevated levels of male hormones (androgens), acne, and hirsutism. It can even cause IR, anovulation, and infertility on prolonging incidence of cysts. One of the treatments for PCOS is the use of synthetic medicine, which can help to treat PCOS but with side effects. However, many women who suffer from PCOS opt to use alternative medicine in conjunction with traditional medicine to improve their condition. There are some herbs that are very helpful in treating PCOS. Since PCOS is a curable disorder, it can be cured by the use of natural remedies or allopathic medication. There is a growing interest in herbal remedies or allopathic medication to cure the PCOS. There is a need to change the lifestyle management, diet to control the PCOS level. The natural remedies include treatment with phytoestrogenic and non-estrogenic herbs such as Licorice, Ginseng, Black cohosh, Dong, soy, evening primrose, honey, fenugreek, Schisandra root, and many other which are effective and safe. Many plants have been highly esteemed sources and have advantages which reduce PCOS and also having a hypoglycemic effect. In this review, an attempt has been made to study the use of natural remedy for the treatment of PCOS.

Highlights

  • Polycystic ovary syndrome (PCOS) is a set of symptoms due to elevated androgens in females

  • An additional consideration reported is that the pattern of gonadotrophin responses to gonadotropin-releasing hormone (GnRH) agonist administration in PCOS women appears to be “masculinized.” Recent data support the hypothesis that perinatal exposure of the neuroendocrine axis to excess levels of androgen may bring about such masculinization by programming the neuroendocrine system to secrete excessive luteinizing hormone (LH) at puberty, resulting in ovarian HA

  • Presence of oligomenorrhea among adolescent girls, 2 years post-menarche, can be a good screening indicator to diagnose a probable case of PCOS as reported earlier

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Summary

INTRODUCTION

Polycystic ovary syndrome (PCOS) is a set of symptoms due to elevated androgens (male hormones) in females. An additional consideration reported is that the pattern of gonadotrophin responses to GnRH agonist administration in PCOS women appears to be “masculinized.” Recent data support the hypothesis that perinatal exposure of the neuroendocrine axis to excess levels of androgen may bring about such masculinization by programming the neuroendocrine system to secrete excessive LH at puberty, resulting in ovarian HA. This hypothesis has been further supported in primate studies, which show that prenatal exposure of female rhesus monkeys to testosterone propionate increases serum LH levels in adulthood.

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