Abstract
AbstractAlphaCor is a new generation of artificial cornea made entirely of pHEMA. It is a flexible 2 part composite device with a transparent centre and a porous skirt, which allows bio‐integration into surrounding host corneal tissue. As a treatment modality AlphaCor exists between traditional keratoprostheses and human donor penetrating keratoplasty. It is most commonly used in high risk corneal regrafts where there is a poor chance of human graft survival.Data has been obtained on every case of AlphaCor implanted, making it the largest series of keratoprostheses published. With this data and resultant alterations in protocol, there has been a gradual decline in the complication rate for this device. The main complications relate to corneal melting, optic deposition, and posterior inflammatory membranes. Because of the design and technique of implantation, post operative glaucoma is uncommon. The probability of retention at one year is 80% and the visual acuity ranges from PL to 6/6 (20/20). The procedure is “reversible” if necessary so the eye is not lost.The data indicates that AlphaCor is an effective alternative to donor corneal transplantation in cases at high risk of graft failure. Excellent visual potential and a wide visual field can be obtained.
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