Abstract
The patent foramen ovale is an intra-cardiac right-to-left shunt that is thought to have an important role in a number of disease processes, including stroke, peripheral embolism, systemic oxygen desaturation (i.e. hypoxaemia) and migraine. A wide variety of percutaneous devices to close congenital heart defects are currently commercially available or in clinical trials. The trend in percutaneous closure of patent foramen ovales is shifting towards defect-tailored devices and new strategies that minimise the amount of foreign material left in the atria. This article focuses on the latest technologies available for closure of patent foramen ovales and on experimental devices currently under investigation.
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