Abstract
Inflammatory choroidal neovascular membranes are challenging to diagnose and manage. A number of uveitic entities may be complicated by the development of choroidal neovascularization leading to a decrease in central visual acuity. In conditions such as punctate inner choroidopathy, development of choroidal neovascularization is extremely common and must be suspected in all cases. On the other hand, in patients with conditions such as serpiginous choroiditis, and multifocal choroiditis, it may be difficult to differentiate between inflammatory choroiditis lesions and choroidal neovascularization. Multimodal imaging analysis, including the recently introduced technology of optical coherence tomography angiography, greatly aid in the diagnosis and management of inflammatory choroidal neovascularization. Management of these neovascular membranes consists of anti-vascular growth factor agents, with or without concomitant anti-inflammatory and/or corticosteroid therapy.
Highlights
Choroidal neovascular membranes (CNV) represent the pathological growth of blood vessels and can result in loss of visual function
fluorescein angiography (FA) in the detection of CNV in inflammatory conditions may be inconclusive. Additional tests such as optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) may be needed to initiate therapy for CNV lesions and a multimodal imaging approach is always recommended
The detection of CNV is challenging in patients with uveitis due to the difficulties of visualizing the lesion amidst choroiditis lesions, scarring, and pigmentation
Summary
An update on inflammatory choroidal neovascularization: epidemiology, multimodal imaging, and management. Aniruddha Agarwal1†, Alessandro Invernizzi2†, Rohan Bir Singh, William Foulsham, Kanika Aggarwal, Sabia Handa, Rupesh Agrawal, Carlos Pavesio and Vishali Gupta1*
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.