Abstract
Puberty is best defined at the period of life during which one acquires reproductive capabilities. As a female transitions from childhood to adulthood, one witnesses a significant reactivation of the hypothalamicpituitary- ovarian (HPO) axis; this axis is functional in utero.The hallmarks of pubertal development include:All this may take three to five years for completion.The American Academy of Pediatrics Pediatric Research in Office Settings (PROS) Study has provided the latest information regarding age of onset of specific pubertal milestones. PROS focused on breast development— thelarche (an early sign of the onset of puberty) occurs in African-American girls at 8.87 years and in white American girls at 9.96 years of age; the onset of pubic and axillary hair development, i.e. pubarche, occurs in African-American girls at 8.78 years and in white girls at 10.51 years of age.1,2Additional information is detailed inTable 1.
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