Abstract
Morphine can mimic effect of ischemia preconditioning and show some beneficial cardioprotective effects on animal hearts undertaken ischemia/reperfusion injury. Morphine preconditioning confers biphasie eardioprotection: early preconditioning and delayed preconditioning. This kind of protection is mostly mediated by opioid receptor, mitochondrial KATP channel, iNOS and COX-2. Beyond the acknowledgement of its molecular mechanism of morphine preconditioning, it is also important to induce related clinical research. Key words: morphine; ischemic preconditioning, myocardial; ischemia/reperfusion injury
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Schedule a callMore From: International Journal of Anesthesiology and Resuscitation
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