An unusually extensive case of Paget's disease of the nipple

Abstract

An unusually extensive case of Paget's disease of the nipple is presented. The patient had concealed the disease for over 10 years and was reluctant to accept treatment. A response was achieved with Tamoxifen. An initial complete response was obtained with radiation therapy, using an electron arc. Several plaques of recurrent disease developed in areas treated with less than 50 Gy, which have been controlled with the addition of superficial X-ray therapy. She remains well and disease-free 9 months following completion of treatment.