An Unusual Variant of Cutaneous Sarcoidosis

Siham Mansouri,Badr Hassam,Asmaa Sqalli,Laila Benzekri,Karima Senouci,Nadia Ismaili

doi:10.23937/2474-3682/1510103

Abstract

Sarcoidosis is a multisystem inflammatory disease of unknown etiology, characterized by noncaseating granuloma variably infiltrating the respiratory tract, ganglions, eyes, internal organs and the skin. The heterogeneity of cutaneous sarcoidosis represents a diagnostic challenge for physicians and affirms its reputation as a 'great imitator'. Common specific lesions associated with sarcoidosis are papules, plaques, nodules, scar sarcoidosis and lupus pernio.

Highlights

Sarcoidosis is a systemic disease characterized by the formation of noncaseating granulomas in several organs
Two cases have been noted in white women, one without systemic involvement at the time of diagnosis [5], our patient presented with disease limited to the skin
Our case confirms the variation of lesions in cutaneous sarcoidosis

Summary

Introduction

Sarcoidosis is a systemic disease characterized by the formation of noncaseating granulomas in several organs. Various cutaneous manifestations of sarcoidosis occur in approximately 25% of patients and may indicate onset of the disease [1]. A 50-year-old Moroccan caucasian female with no history of systemic sarcoidosis, presented with a 6-month history of a nodular verrucous lesion of 3 cm of diameter on the nose (Figure 1). The patient consulted a surgeon who performed a total lesion excision without prior skin biopsy, thinking it may be a squamous cell carcinoma. Histology revealed noncaseating granuloma giganto-cellular with a sparse lymphocytic infiltrate of the dermis (Figure 2). The patient had no systemic involvement and was treated with topical and systemic corticosteroids (0.7 mg/kg/day) with good clinical development after 03 months (Figure 4)

Discussion

Findings

Conclusion