Abstract
Hereditary angioedema (HAE) is a rare disease characterized by repeated episodes of bradykinergic-driven angioedema that can involve the oral mucosa, pharynx, larynx, gastrointestinal system, and extremities.1 The prevalence estimates for HAE range between 1 in 10,0002 and 1 in 150,000.3 HAE is categorized into the following 3 distinct subtypes: (1) HAE type I, the most common type, with a reduced quantity of C1 esterase inhibitor protein; (2) HAE type II, with decreased function of C1 esterase inhibitor protein; and (3) HAE with normal C1-inhibitor function (HAE nC1-INH) (previously known as HAE type III).
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