Abstract
AbstractPrimary non-epithelial malignancies of the penis are rare. We report a patient with an unusual presentation of an unexpected spindle cell malignancy at this site. A 35- year-old man presented with a mass in the shaft of the penis with inguinal lymphadenopathy. A malignant spindle cell neoplasm was seen involving the corpora, consistent with leiomyosarcoma. Immunohistochemically, the tumour was positive for S100, HMB-45 and negative for SMA. A final diagnosis of amelanotic spindle cell melanoma was made. This case is being presented to reiterate the importance of including melanoma in the differential diagnosis of spindle cell sarcomas at uncommon sites.
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