Abstract
Although epitrochlear lymph nodes may be enlarged as a part of generalized lymphadenopathy, isolated enlargement of epitrochlear lymph nodes is rarely seen. We describe Hodgkin’s lymphoma in a 55-year-old male who presented with isolated epitrochlear lymphadenopathy of his right arm. In the histopathological examination of the epitrochlear lymph node was a lymphocyte-rich Hodgkin lymphoma with a clinical grade (CS IA) diagnosed. The diagnosis was confirmed, via the bone marrow biopsy and positron emission tomography/computed tomography imaging, as pathological stage PS IA and clinical stage CS IA. Epitrochlear lymph node involvement, as a first presentation, is rarely seen in Hodgkin’s lymphoma. The aim of this study was to recapitulate the possible background diseases arising on the basis of an asymptomatic epitrochlear lymphadenopathy, to review the Hodgkin lymphoma presenting with primary epitrochlear lymphadenopathy in light of the literature, and to highlight the importance of a careful examination of the elbow site in routine physical examination.
Highlights
IntroductionEpitrochlear lymph nodes, which are nonpalpable normally, generally become palpable as a result of a pathological disease.[1]
Epitrochlear region lymphadenopathies are observed in forearm and hand pathologies
Epitrochlear lymphadenopathy is frequently a component of generalized lymphadenopathy; it may be manifested as an isolated form
Summary
Epitrochlear lymph nodes, which are nonpalpable normally, generally become palpable as a result of a pathological disease.[1]. Epitrochlear lymphadenopathy is frequently a component of generalized lymphadenopathy; it may be manifested as an isolated form. Lymphoma and malignant melanoma may be counted as malignant involvements. Epitrochlear lymph node involvement is a very rarely detected finding in both Hodgkin and non-Hodgkin lymphoma. A 2-cm sized solid, medium hard, palpable mass was detected in the medial aspect of the right forearm in the physical examination. Ultrasound (US) examination revealed a 16 × 12 × 10 mm sized, ill-defined, oval and hypoechoic lymph node without hilar hyperechoic structure. Excisional biopsy of epitrochlear lymph node was performed under general anesthesia. Histopathological examination revealed lymphoid follicles (CD23) with significant germinal centers and significantly widened mantle zones in the lymph node.
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