An unusual cleavage of a C–S bond with concurrent S-arylation under palladium–copper catalysis

Abstract

3-[2-( N- p-Toluenesulfonyl)aminophenylthio]prop-1-yne ( 4) reacted with aryl iodides 5– 14 under palladium–copper catalysis to afford (2-arylthio)- p-toluenesulfonanilide ( 15– 23) in moderate to good yields (54–64%) through unusual depropargylation and S-arylation reactions.