Abstract
BackgroundCastleman disease (CD) is a group of rare lymphoproliferative diseases with common lymph node histological features that can easily be misdiagnosed as infections, multiple autoimmune diseases, and malignant tumors.Case presentationHere we report a rare case of a Chinese male with refractory ascites for two years and was eventually diagnosed as CD.ConclusionsThe challenges in diagnosis of CD arise from the large differential, clinical heterogeneity and our limited understanding of pathology. In case of rare ascites, CD needs to be considered.
Highlights
Castleman disease (CD) is a group of rare lymphoproliferative diseases with common lymph node histological features that can be misdiagnosed as infections, multiple autoimmune diseases, and malignant tumors.Case presentation: Here we report a rare case of a Chinese male with refractory ascites for two years and was eventually diagnosed as CD
This case report provides a valuable reference for the diagnosis and treatment of CD and rare ascites
CD is clinically divided into unicentric CD (UCD), which is characterised by an asymptomatic mass in patients with one area of lymphadenopathy, and multicentric CD (MCD), which is characterised by constitutional symptoms, multicentric lymphadenopathy, hepatosplenomegaly and laboratory abnormalities such as anemia, hypergamma globulinemia, and bone marrow plasmacytosis [2]
Summary
Castleman disease (CD) is a group of rare lymphoproliferative diseases with common lymph node histological features that can be misdiagnosed as infections, multiple autoimmune diseases, and malignant tumors.Case presentation: Here we report a rare case of a Chinese male with refractory ascites for two years and was eventually diagnosed as CD. We introduce a case of a patient who was diagnosed as CD in the gastroenterology department of our hospital due to refractory ascites. This case report provides a valuable reference for the diagnosis and treatment of CD and rare ascites.
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