Abstract
Preeclampsia/eclampsia is a serious complication of the pregnancy and early-onset disease is mostly associated with molar pregnancy. We present a rare case of eclampsia that occurred at very early weeks of gestation and had multiple risk factors for preeclampsia, but not molar pregnancy. A 35-year-old woman (gravidity 11, parity 1) presented with eclampsia at 21 weeks of gestation. She had history of preeclampsia in previous pregnancy, chronic hypertension, recurrent pregnancy loss (a total of 9 abortions at 6-21 weeks of gestation) and methyltetrahydrofolatereductase (MTHFR) heterozygous mutation. The pregnancy was terminated by hysterotomy. Molar change was not observed in the placenta. No postoperative complication occurred and the patient was discharged with antihypertensive therapy. Eclampsia is a severe form of the preeclampsia and clinicians should keep in mind that it may be occurred at very early weeks of gestation in patients with multiple risk factors for preeclampsia.
Highlights
Preeclampsia is a leading cause of the maternal and perinatal morbidity and mortality [1]
Many risk factors associated with preeclampsia such as older maternal age, nulliparity, obesity, multifetal gestation, previous preeclampsia, chronic hypertension, diabetes mellitus, molar pregnancy, chronic autoimmune disease, and renal disease have clarified [1]
It usually occurs last trimester of pregnancy and may emerge at antepartum, intrapartum and postpartum period [2].Unlike the literature, we presented an unusual eclampsia case with multiple risk factors occurred at 21 weeks of gestation, much earlier than expected weeks
Summary
Preeclampsia is a leading cause of the maternal and perinatal morbidity and mortality [1]. Etiology of preeclampsia is not known exactly. Many risk factors associated with preeclampsia such as older maternal age, nulliparity, obesity, multifetal gestation, previous preeclampsia, chronic hypertension, diabetes mellitus, molar pregnancy, chronic autoimmune disease, and renal disease have clarified [1]. Eclampsia is the severe form of preeclampsia and characterized by convulsions in patients with preeclampsia findings. It usually occurs last trimester of pregnancy and may emerge at antepartum, intrapartum and postpartum period [2].Unlike the literature, we presented an unusual eclampsia case with multiple risk factors occurred at 21 weeks of gestation, much earlier than expected weeks
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