Abstract
Received April 2007 Accepted October 2007 INTRODUCTION Recent investigations of the underlying pathophysiology of renal cell carcinoma (RCC) has resulted in the identification of involved molecular pathways, including the inactivation of the von Hippel-Lindau gene in most sporadic cases of RCC.(1) They are characterized by one specific histological type. In contrast, kidney tumors in patients with Birt-Hogg-Dube syndrome (BHD) consist of a variety of histological types.(2) We report a patient with multiple renal cell tumors in one kidney with a history of spontaneous pneumothorax, but without skin lesions which are typical signs of BHD syndrome.
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