Abstract

IntroductionMalakoplakia is an unusual chronic inflammatory disease. Malakoplakia of the bladder and ureter is quite rare.Case presentationWe present a case of a young male diagnosed as malakoplakia of urinary bladder and ureter. He presented with bilateral hydroureteronephrosis. The patient underwent left ureterocystotomy. Again, he was admitted after a gap of ten years and with features of end stage renal disease.ConclusionThis rare case of urinary bladder and ureter malakoplakia in a young male is presented, to stress upon the fact that though it is a chronic inflammatory disease, yet its outcome over the years is dismal.

Highlights

  • Malakoplakia is an unusual chronic inflammatory disease, which presents as a plaque or a nodule

  • Patients of any age may develop malakoplakia, but the peak occurrence is in middle age

  • We hereby present an unusual case of a young male diagnosed as malakoplakia of urinary bladder and ureter with bilateral hydroureteronephrosis, which progressed to end stage renal disease over a period of ten years highlighting the pathological aspects as histopathology is important in establishing diagnosis

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Summary

Introduction

Malakoplakia is an unusual chronic inflammatory disease, which presents as a plaque or a nodule. We hereby present an unusual case of a young male diagnosed as malakoplakia of urinary bladder and ureter with bilateral hydroureteronephrosis, which progressed to end stage renal disease over a period of ten years highlighting the pathological aspects as histopathology is important in establishing diagnosis. Case presentation An 18-year-old Indian male presented with history of lowgrade fever and bilateral pedal edema for about one and half months in 1995. Histopathological examination of excised distal segment of left lower ureter revealed malakoplakia (Figure 5). He was put on suppressive antibiotics and advised regular follow-up but was lost for follow-up after six months. Ultrasound revealed normal sized right kidney with echogenic cortex and loss of corticomedullary distinction, left kidney contracted with increased echoes

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