Abstract
BackgroundChoroid plexus papillomas (CPPs) are histopathologically benign and rare central nervous system tumors. These tumors remain more frequent in children than adults. It is infrequent for these tumors to cause a sudden unexpected death. We aim in this case to discuss the unusual and fatal presentation of choroid plexus papilloma and the mechanism of death.Case presentationwe report the case of a 61-year-old man with no medical history, diagnosed at autopsy with a previously unknown CPP. Initial complaints were chronic headache occurring in the last month and acute chest pain for two days. The forensic autopsy including the histopathologic examination showed a tumoral mass of the choroid plexus in the fourth ventricle diagnosed as a psammomatous CPP. The cause of death in this case was attributed to a massive cerebral edema caused by the tumoral mass.ConclusionsThrough this case report, we stress the importance of an early and a vigorous investigation of every headache and an early detection of this tumor and we highlight as well the role of the post mortem examination to detect such a fatal complication.
Highlights
BackgroundChoroid plexus papillomas (CPPs) are benign neoplasms representing less than 1% of intracranial tumors (Sodhi et al 2013)
Choroid plexus papillomas (CPPs) are histopathologically benign and rare central nervous system tumors
Choroid plexus papillomas (CPPs) are benign neoplasms representing less than 1% of intracranial tumors (Sodhi et al 2013)
Summary
Choroid plexus papillomas (CPPs) are benign neoplasms representing less than 1% of intracranial tumors (Sodhi et al 2013). Case presentation A 61-year-old man with no medical history had been suffering from an intermittent headache for 1 month and chest pain for 2 days before coming to the hospital On the admission, his neurological state deteriorated and he died before undergoing any explorations. A mass of the choroid plexus was found in the fourth ventricle measuring 0.8 × 1 cm (Fig. 1). This mass was taken for histopathologic analysis as well as samples from all the organs. The histological examination of the rest of the brain tissue showed foci of cerebral edema and did not show any signs of malignancy. The cause of death was attributed to cerebral edema due to choroid plexus papilloma
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