Abstract
Langerhans cells, identified by the presence of the characteristic granule, were found in oral lichen planus lesions, both within the epithelium and in the inflammatory cell infiltrate of the connective tissue. They varied in numbers in different specimens and also in different areas of the same specimen. They were most numerous in the prickle cell layer. However, where Langerhans cells were increased, some were in the basal cell region, some extended through the basal complex and some lay wholly within the connective tissue infiltrate. The present findings suggest that Langerhans cells are capable of moving freely from the epithelium to the connective tissue and vice versa.
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