Abstract
Schiff base compounds are called relative to the scientist who first prepared them (Hugo Schiff). They are synthesized by the condensation reaction of the carbonyl group –C=O– of the aldehyde or ketone compound with a primary amine. This leads to the formation of azomethine or imine group –C=N– plus water molecule. Schiff base molecules have gained special importance due to their biological activity, such as anti-inflammatory and antibiotic. Schiff base compounds are also utilized in the industry as corrosion inhibitors, dyes, and photo-stabilizers of plastic polymers. This short review includes highlighting of recent approaches of synthesis novel Schiff base molecules. It also discusses the mechanism of the reaction and why it is a reversible condensation reaction.
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