An overview on nanobased drug delivery system

Abstract

There has been considerable interest in drug delivery research over the past few decades using particulate delivery systems as carriers for large and small molecules. Particulate structures such as nanoparticles were used as a physical method to modify and enhance the pharmacokinetic and pharmacodynamic properties of different types of drug molecules. Nanoparticles (NP) are classified as particles with a diameter of less than 100 nm and are increasingly used in various applications, including drug carrier systems, passing through barriers to organs such as the blood-brain barrier. Due to their unique properties, nanocrystals (quantum dots) and other nanoparticles (gold colloids, nanobars, dendrimers and nanoshells) have received a great deal of attention for possible use in Therapeutics and therapeutic drug discovery. The use of nanotechnology in medicine is expected to spread rapidly, and more precisely, the delivery of drugs. Several drugs are currently under investigation for drug delivery and cancer therapy in particular. Ironically, pharmaceutical sciences use nanoparticles to minimize the toxicity and side effects of drugs, and they have not realized until recently that carrier systems can impose risks on the patient themselves. All these aspects of NP are discussed in the present article.