AN OVERVIEW OF SYSTEMIC IMMUNE-INFLAMMATION INDEX AND HEMATOLOGICAL LABORATORY FINDINGS IN FIBROMYALGIA SYNDROME

Abstract

This study aimed to determine disease activity by evaluating the relationship between the Systemic Immune-Inflammation Index (SII) and blood parameters in fibromyalgia syndrome (FMS). 109 FMS patients and 82 healthy controls were included in this retrospective study. Age, gender, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), white blood cell (WBC), hemoglobin (HGB), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red cell distribution (RDW), platelet distribution width (PDW), mean platelet volume (MPV), platelet (PLT), platelet crit (PCT), lymphocyte (LYM), monocyte (MONO), neutrophil (NEU) levels were scanned retrospectively from the hospital information system. Platelet-lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), and SII were calculated. CRP and ESR levels were elevated in fibromyalgia (FMS) patients compared to healthy controls, although they remained within the standard value range (p