An overview of surgical site infection and prophylactic antibiotics in vascular surgery

Abstract

Background: Vascular surgery is a complex procedure with many complications such as surgical site infections, graft infections, pneumonia, myocardial infarction, hemorrhage, and thromboembolism or thrombosis, in which, the most common complications are surgical site infection, and graft infection. Currently, antibiotic prophylaxis is considered the most effective practice to suppress surgical site infection in surgical procedures including vascular surgery. The aim of this paper is to review the surgical site infection and prophylactic antibiotics in vascular surgery.[1]
 Method: A search was made by using Medline, PubMed, Scopus and Web of Science databases, and databases of journals in Vietnam.
 Result: 1227 records were identified, of which 112 were included in this review. This included 90 researches, and 22 guidelines.
 Conclusion: In vascular surgery, antibiotic prophylaxis is recommended in most guidelines for abdominal aortic surgery, lower limb vascular surgery, vascular surgery with prosthetic grafts or stents. The common antibiotic regimens are 1st generation cephalosporins – C1G (cefazolin), 2nd generation cephalosporins – C2G (cefuroxim) administrated 60 minutes before incision, and discontinued within 24 hours of surgery.