Abstract
Evidence supports hyperexcitability as a cause of migraine in the affected brain. This hyperexcitability may have its origins in many factors including low magnesium levels in serum, cerebrospinal and other fluids, mitochondrial and energy metabolism abnormalities, excessive nitric oxide levels or sensitivity to nitric oxide, and channel protein mutations. New imaging technologies, such as positron-emission tomography, have provided clues to the sequence of events in migraine and may offer clues for developing additional avenues of treatment. Better understanding of the physiologic and molecular events in migraine may lead to even better targets for therapy.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
