An Overview of Infection in Bone Marrow Transplant Recipients

Abstract

To investigate the imaging features of a reversible lesion in the splenium of corpus callosum related to encephalitis/encephalopathy in children.A retrospective analysis was performed on the MRI findings of 84 children suffering from mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) during different infection processes, and the imaging characteristics of the lesion on diffusion weighted image (DWI) were analyzed.In the 84 children with MERS, 42 children had upper respiratory tract infection, 33 children had enteritis, 9 children had upper respiratory infection accompanied by enteritis. Among them, 76 cases were of type I, with round or oval lesions in the splenium of corpus callosum, the other 8 cases were of type II, with lesions not only in the splenium of the corpus callosum, but also in the genu of the corpus callosum and in the periventricular white matter. The splenial lesions exhibited high-intensity on the diffusion-weight imaging with low ADC value on the ADC map. The abnormal signal disappeared and normalized in 3–15 days.There are three types of common infection could cause mild encephalitis/encephalopathy with a reversible splenial lesion in children. Reduced diffusion in the splenium of the corpus callosum on DWI proved to be a specific finding that could be used to guide clinical treatment.