An overview of eosinophilic esophagitis in children

Abstract

Based on the patient's age, eosinophilic esophagitis (EE) has different clinical manifestations. Infants and young children frequently have vague manifestations such difficulty eating, nausea, and discomfort in the abdomen. Despite having symptoms that resemble gastroesophageal reflux, children with EE, do not respond to intensive ant reflux medication. Dysphagia and food impaction became the most common symptoms in adults and adolescents. EE should also be considered when treating adults and children who continue to have heartburn. Pediatric and adult patients frequently have concurrent allergy disorders such asthma, rhinitis, and eczema, in addition to peripheral eosinophilia and increased total blood IgE levels. Mucosal oedema, furrows, exudates, corrugated bands, strictures, and the alleged "crepe paper sign" are some of the endoscopic characteristics of EE. EE is widely seen as a distinct condition from reflux disorder. According to current understanding, the former could be a symptom of eosinophilic gastroenteritis or be induced by cell-mediated food hypersensitivity. Reports back up the effectiveness of steroid treatment or food restriction. To ascertain the cause, enable early clinical identification, and enhance treatment, more research is required.