An outbreak of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemase in western China

Abstract

Twenty-two non-repetitive carbapenem-resistant Acinetobacter baumannii isolates were obtained from Intensive Care Unit patients. All of the isolates carried bla OXA-23, bla OXA-66, a novel cephalosporinase-encoding gene ( bla ADC-25) and a class 1 integron with an aacC1–orfP–orfQ– aadA1a cassette array and had identical enterobacterial repetitive intergenic consensus (ERIC) profiles. ISAba 1 was found upstream of bla OXA-23, but was not associated with bla OXA-66 or bla ADC-25.