Abstract
Urea has come into extensive clinical use as an ocular hypotensive agent. However, investigation of other osmotic compounds continues. While recent studies have dealt with the use of mannitol as a diuretic and for lowering cerebrospinal fluid pressure, no comprehensive analysis of its effect on ocular pressure has appeared. This com munication reports a study designed to eval uate mannitol as an ocular hypotensive agent, and to compare its efficacy in this re gard with that of urea.
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