An Opportunity for Management of Fatigue, Physical Condition, and Quality of Life Through Asynchronous Telerehabilitation in Patients After Acute Coronavirus Disease 2019: A Randomized Controlled Pilot Study

Abstract

ObjectiveTo compare the preliminary efficacy of asynchronous telerehabilitation in patients after acute coronavirus disease 2019 (COVID-19) on fatigue, physical condition, quality of life, and feasibility of this pilot study with that of a booklet format. DesignRandomized pilot study with 2 intervention arms: asynchronous telerehabilitation group and booklet-based rehabilitation group, with 2 follow-ups at 3 and 6 months. SettingHospital. ParticipantsPatients discharged after COVID-19 were recruited and evaluated (N=35). InterventionsThe intervention consisted of a 12-week multimodal rehabilitation program via telerehabilitation or by a booklet. Main Outcome MeasuresFatigue as the main outcome and functional status, quality of life, and feasibility as secondary outcomes were evaluated. ResultsAfter the intervention, there was no significant difference between groups in fatigue, but there were significant differences in favor of the asynchronous telerehabilitation group for the 6-Minute Walk Test (p=.008), the 30-Second Sit-to-Stand Test (p=.019), and physical quality of life (p=.035). These improvements were maintained throughout the 6-month follow-up. Telerehabilitation was shown to be a viable option, without incidents and with a higher adhesion (p=.028) than the booklet format. ConclusionsA multimodal rehabilitation program by means of asynchronous telerehabilitation appears as a more effective option than traditional formats in improving post–acute COVID-19 sequelae.