AN OPERATING CASE OF LUNG CANCER WITH MYELODISPLASTIC SYNDROME (MDS)

Abstract

A 75-year-old man was admitted to the hospital because of a suspected lung cancer at routine chest X-ray examination. Tracheobronchoscopy and transbronchial lung biopsy demonstrated squamous cell carcinoma of the right upper lobe. His peripheral blood count showed pancytopenia and he was diagnosed as myelodysplastic syndrome (MDS), refractory anemia, based on dysplastic findings of the bone marrow. He received perioperative transfusion of packed red blood cells and platelets, and recombinant human granulocyte colony-stimulating factor (rhG-CSF) was added. Right upper lobectomy and mediastinal-hilar lymph node dissection were carried out. After the operation he was successfully treated with antibiotics and rhG-CSF for postoperative pneumoniae. He is now doing well with no evidence of recurrence, as of 18 months after the surgery. An operating case of lung cancer with MDS is described with a review of the literatutre. It is considered that perioperative management with transfusion and rhG-CSF is reasonable for MDS patients.