Abstract
Cardiovascular disease is the main causes of morbidity and mortality due to lumen stenosis and atherosclerosis. Intravascular ultrasound (IVUS) is able to delineate internal structures of vessel wall with fine spatial resolution. However, IVUS is insufficient to identify the fibrous cap thickness and tissue composition of atherosclerotic lesions, the key factors to stage atherosclerosis and determine appropriate treatment strategies. Currently, novel techniques have been developed to determine tissue composition, which require an open IVUS system to accommodate these techniques for comprehensive plaque characterization. This paper presents the development of such an IVUS system with reconfigurable hardware implementation, programmable image processing algorithms, and flexible imaging control to support an easy fusion with other techniques to improve the diagnostic capabilities for cardiovascular diseases. In addition, this IVUS utilized a miniaturized ultrasound transducer constructed by PMN-PT single cry...
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