Abstract

To compare efficacy of intravenous dexmedetomidine versus butorphanol for balanced anaesthesia and postoperative analgesia in patients undergoing laparoscopic surgery under general anaesthesia. After obtaining institutional ethical committee approval & written informed consent 54 adults of either gender aged 18-60 years, of grade I & II ASA were divided into two equal groups; Group D received Inj. Dexmedetomidine 1 µg/kg i.v. & Group B, Inj. Butorphanol 10 µg/kg i.v., in 100ml NS over 10 minutes before induction. Standard general anaesthesia technique including propofol, succinylcholine/Atracurium, IPPV & Isoflurane/N20 was administered. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) & SPO2 were recorded at - baseline, after-drug administration, induction, at intubation & 1, 3 & 5 minutes after intubation, at pneumoperitoneum & 15 minutes intervals upto 30 minutes after extubation. Postoperative Visual Analog Scale (VAS) Scores & Ramsay Sedation Score (RSS) were evaluated half hourly till score of >4 & <2 were recorded, respectively.

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