An observational study of pressure regulated volume control ventilation mode in cardio-pulmonary resuscitated patients

Abstract

Objective To observe the effects of pressure regulated volume control (PRVC) ventilation mode in cardio-pulmonary resuscitated patients. Methods Thirty-five adult patients who suffered from cardiorespiratory arrest were PRVC ventilated and so called PRVC-group. An retrospective collection of another 70 adult patients who suffered from cardiorespiratory arrest were divided into two groups according to the ventilation mode the received: PCV (pressure controlled ventilation) -group (n=35) and VCV (volume control ventilation)-group (n=35). The arterial partial pressure of oxygen (PaO2), arterial carbon dioxide partial pressure (PaCO2), oxygenation index (OI), heart rate (HR), mean arterial pressure (MAP), central venous pressure (CVP) and peak inspimtory pressure (PIP) of the patients after successful resuscitation of spontaneous circulation (ROSC) in each group were analyzed by One-Way AVOVA. The index would be further analyzed using Student-Newman-Keuls (SNK) if statistically significant. The ROSC rates in the three groups were analyzed by chi-square test. Results (1)The ROSC rate in PRVC-group is higher than in PCV-group or VCV-group, with statistical significance (χ2=6.533, P<0.05). (2)The PaO2 and OI in PRVC-group is higher than those in PCV-group and in VCV-group (F=19.601, 31.562, P<0.05), while the CVP and PIP in PRVC-group is lower than those in PCV-group and in VCV-group (F=12.045, 8.340, P<0.05), and PaCO2, HR and MAP among these three groups have no statistically significant difference. Conclusions PRVC ventilation may help with a higher successful ROSC rate in cardio-pulmonary resuscitated patients due to its good ventilation support. Moreover, it can preferably improve oxygenation with little influence on hemodynamics, which also facilitate the success rate of cardio-pulmonary resuscitation. Key words: Cardio-pulmonary resuscitation; Mechanical ventilation; Pressure regulated volume control ventilation