Abstract
Intraventricular Hemorrhage (IVH) is a serious neurovascular complication in neonates that can lead to blood clots forming in the ventricular system [1]. Magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) has been investigated as a non- invasive treatment for clot lysis [2][3]. However, current MRgHIFU systems are not suitable for treating IVH in neonates. We have developed an MRgHIFU platform optimized for the neonatal brain, which facilitates ergonomic patient positioning and directs treatment through their anterior fontanelle. This platform is based on an MRI-compatible robot designed by our group [4]. This paper describes the optimization of the MRgHIFU platform and its initial validation for treating IVH.
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